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What is methanol? How does it get into drinks and cause harm?

<div class="theconversation-article-body"><a href="https://theconversation.com/profiles/ian-musgrave-1808">Ian Musgrave</a>, <a href="https://theconversation.com/institutions/university-of-adelaide-1119">University of Adelaide</a> Melbourne teenager Bianca Jones <a href="https://www.abc.net.au/news/2024-11-21/bianca-jones-dead-laos-methanol-poisoning/104630384">has died</a> and her friend Holly Bowles remains severely ill in hospital in Thailand, after experiencing suspected methanol poisoning while they were travelling in Laos. The pair are reportedly among <a href="https://x.com/Smartraveller/status/1858850858227954118">several foreign nationals</a> who became ill after unknowingly consuming alcoholic drinks containing methanol in the south-east Asian country. So what is methanol, and how does it make people sick? <h2>Methanol versus ethanol</h2> <a href="https://en.wikipedia.org/wiki/Methanol">Methanol</a> is an <a href="https://en.wikipedia.org/wiki/Alcohol_(chemistry)">alcohol</a>, like the familiar <a href="https://en.wikipedia.org/wiki/Ethanol">ethanol</a> we consume in alcoholic beverages. Like ethanol, methanol is a colourless, flammable liquid. It has a smell similar to ethanol as well. But the two have different chemical structures. Methanol is composed of only one carbon atom, while ethanol has two. <figure class="align-center "><img src="https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=45&auto=format&w=754&fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=45&auto=format&w=600&h=300&fit=crop&dpr=1 600w, https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=30&auto=format&w=600&h=300&fit=crop&dpr=2 1200w, https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=15&auto=format&w=600&h=300&fit=crop&dpr=3 1800w, https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=45&auto=format&w=754&h=377&fit=crop&dpr=1 754w, https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=30&auto=format&w=754&h=377&fit=crop&dpr=2 1508w, https://images.theconversation.com/files/633188/original/file-20241120-15-i7wr12.png?ixlib=rb-4.1.0&q=15&auto=format&w=754&h=377&fit=crop&dpr=3 2262w" alt="Models of methanol and ethanol depicted with balls and sticks." /><figcaption>Methanol (left) and ethanol (right) have differing chemical structures. Wikimedia Commons, <a class="license" href="http://creativecommons.org/licenses/by/4.0/">CC BY</a></figcaption></figure> That one carbon atom makes all the difference. It means methanol is processed differently in our bodies and is much more toxic than ethanol. Methanol is used in a <a href="https://pubchem.ncbi.nlm.nih.gov/compound/Methanol">variety of industrial and household products</a>, such as windshield cleaning fluids, antifreeze and fuel. It’s not safe for human consumption. <h2>What makes methanol toxic?</h2> The difference is in how methanol is metabolised, or broken down in our bodies. Ethanol is metabolised into a chemical compound called acetaldehyde. Acetaldehyde is toxic, but is rapidly converted to acetate (also known as acetic acid, found in vinegar). Generating an acid may sound bad, but acetate actually <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6699882/">produces energy and makes important molecules</a> in the body. By contrast, methanol is metabolised into <a href="https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/formaldehyde">formaldehyde</a> (a chemical used in <a href="https://www.safework.nsw.gov.au/hazards-a-z/hazardous-chemical/priority-chemicals/formaldehyde">industrial glues</a> and for embalming corpses, for example) and then to <a href="https://pubchem.ncbi.nlm.nih.gov/compound/Formic-Acid">formic acid</a> (the chemical in some ant bites that makes them hurt so much). Unlike acetate, which the body uses, formic acid <a href="https://pubmed.ncbi.nlm.nih.gov/1665561/">poisons the mitochondria</a>, the powerhouses of the cells. As a result, a person exposed to methanol can go into severe <a href="https://www.ncbi.nlm.nih.gov/books/NBK482121/">metabolic acidosis</a>, which is when too much acid builds up in the body. Methanol poisoning can cause nausea, vomiting, and abdominal pain. The acidosis then causes depression of the central nervous system which can cause people with methanol poisoning to fall unconscious and go into a coma, as well as retinal damage leading to vision loss. This is because the retinas are full of active mitochondria and sensitive to them being damaged. Death is not inevitable if only a small amount of methanol has been consumed, and rapid treatment will greatly reduce damage. However, permanent vision damage can occur even at <a href="https://www.ncbi.nlm.nih.gov/books/NBK482121/">non-lethal doses</a> if treatment is not administered quickly. <h2>What does treatment involve?</h2> <a href="https://www.ncbi.nlm.nih.gov/books/NBK482121/">Treatment</a> is mainly supportive care, such as intubation and mechanical ventilation to help the patient to breathe. But it can also involve drugs such as <a href="https://go.drugbank.com/drugs/DB01213">fomepizole</a> (which inhibits the generation of toxic formic acid) and dialysis to remove methanol and its metabolites from the body. <h2>How does methanol get into alcoholic drinks?</h2> Methanol can turn up in any alcoholic beverage, but it’s most likely in beverages with higher alcohol content, such as spirits, and traditionally brewed drinks, such as fruit wines. Methanol can get into alcoholic beverages in a number of ways. Sometimes it’s added <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8303512/">deliberately and illegally</a> during or after manufacturing as a cheaper way to increase the alcohol content in a drink. <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5028366/">Traditional brewing methods</a> can also inadvertently generate methanol as well as ethanol and produce toxic levels of methanol depending on the microbes and the types of plant materials used in the fermentation process. We don’t yet know how the Australian teenagers came to be poisoned in this tragedy. But it is a good idea when travelling (particularly in areas with traditionally fremented drinks, such as south-east Asia, the Indian subcontinent and parts of Africa) to always be careful. The Australian government’s <a href="https://www.smartraveller.gov.au/before-you-go/safety/partying#methanol">Smartraveller website</a> advises that to avoid methanol poisoning you should be careful drinking cocktails and drinks made with spirits, drink only at reputable licensed premises and avoid home-made alcoholic drinks. Drinking only mass-produced commercial brews can be safer, though understandably people often want to try locally made drinks as part of their adventure.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/244151/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/ian-musgrave-1808">Ian Musgrave</a>, Senior lecturer in Pharmacology, <a href="https://theconversation.com/institutions/university-of-adelaide-1119">University of Adelaide</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-is-methanol-how-does-it-get-into-drinks-and-cause-harm-244151">original article</a>. </div>

Body

Fifth death confirmed in Laos poisoning

A young British lawyer has died in hospital after a suspected mass poisoning that has claimed the lives of four others. On Thursday, Melbourne teen Bianca Jones became the fourth person to die from suspected methanol poisoning following the deaths of two Danish women and an American who had all been holidaying in the in the party town of Vang Vieng. Lawyer Simone White, 28, was among a dozen other tourists taken to hospital after visiting the backpacker town, with Thai police confirming her death on Friday morning. In a statement to <a href="https://7news.com.au/news/british-lawyer-simone-white-in-hospital-after-apparent-mass-methanol-poisoning-in-laos-c-16833986" target="_blank" rel="noopener">7News</a>, a spokesperson for Britain’s Foreign, Commonwealth and Development Office confirmed a death in Laos, saying, “We are supporting the family of a British woman who has died in Laos, and we are in contact with the local authorities.” Her friend Bethany Clarke, who was with White on holiday, urged tourists in the region to “avoid all local spirits” after their group of six fell ill. “Our group stayed in Vang Vieng and we drank free shots offered by one of the bars. Just avoid them as so not worth it,” she wrote in a Laos backpacking Facebook group. “Six of us who drank from the same place are in hospital currently with methanol poisoning.” Australian Prime Minister Anthony Albanese paid tribute to Jones, 19, in federal parliament on Thursday after news of her death was shared, as her friend Holly Bowles continues to fight for her life in a Bangkok hospital. “This is every parent’s very worst fear and a nightmare that no one should have to endure,” Albanese said. Image credits: Facebook

Caring

"Every parent's nightmare": Families of poisoned teens share update

The families of Holly Bowles and Bianca Jones have shared a heartbreaking update as the teenagers continue to fight for their lives after being <a href="https://oversixty.com.au/travel/travel-trouble/two-aussie-teens-poisoned-in-laos-identified" target="_blank" rel="noopener">poisoned</a> in Laos. While travelling around south-east Asia on a gap year, the Melbourne 19 year olds consumed what is believed to be methanol-laced drinks in Laos. The young women were found barely alive in their hotel room and were rushed to a hospital in the neighbouring country of Thailand, where they remain on life support. Holly’s dad Shaun Bowles fronted the media on Wednesday in Bangkok where he confirmed his daughter remained in the ICU in a critical condition, where the family are spending as much time as possible by her bedside. “Right now our daughter remains in the intensive care unit in a critical condition. She’s on life support,” Shaun said. “We’d just like to thank everyone from back home for all the support and love that we’re receiving but we’d also like for people to appreciate right now we just need privacy so we can spend as much time as we can with Holly.” Bianca's family also released a statement saying there was no update on her condition, but confirmed that she remains on life support. "Our family has been overwhelmed by the messages of love and support that have come from across Australia," the statement from the family reads. "This is every parent's nightmare and we want to ensure no other family is forced to endure the anguish we are going through. We hope the authorities can get to the bottom of what happened as soon as possible." Authorities suspect the girls drank poisoned cocktails which reportedly had shots of "vodka" while holidaying in the party town of Vang Vieng, a popular tourist area about 130km north of Laos capital, Vientiane. They were among a large group of international travellers who fell victim to what is feared to be a mass poisoning which has already killed two other people. Editor's note: Police in Thailand confirmed the death of Bianca Jones on Thursday afternoon. Holly Bowles is understood to still be in hospital. Image credits: Facebook

Caring

Two Aussie teens poisoned in Laos identified

Two Australian teenagers who are fighting for their lives in a hospital in Thailand have been identified. While travelling around south-east Asia on a gap year, Melbourne teens Holly Bowles and Bianca Jones, both aged 19, consumed what is believed to be methanol-laced drinks in Laos. The young women were found barely alive in their hotel room and were rushed to a hospital in the neighbouring country of Thailand, where they remain on life support. Authorities suspect the girls drank poisoned cocktails which reportedly had shots of "vodka" while holidaying in the party town of Vang Vieng, a popular tourist area about 130km north of Laos capital, Vientiane. They were among a large group of international travellers who fell victim to what is feared to be a mass poisoning which has already killed two other people. Ms Jones’ family has expressed disbelief in what has happened to their daughter, describing her as their "angel" as they rushed to be at her bedside. "Our beautiful Bianca was on a dream getaway with her best friend Holly," they told the <a href="https://www.heraldsun.com.au/news/victoria/two-melbourne-girls-on-life-support-in-bangkok-after-ethanol-poisoning-in-laos/news-story/6194b29655744b3f1bceeab2980c8e83" target="_blank" rel="nofollow noreferrer noopener">Herald Sun</a>. "They were filled with joy and had such incredible adventures ahead of them, travelling through Asia. We are here by Bianca’s bedside praying for her." "She's just an absolute star. She's a bundle of joy. To know her is to love her," the cafe manager told <a title="The Age" href="https://www.theage.com.au/national/victoria/fears-for-absolute-star-as-teens-fight-for-life-in-thailand-after-alcohol-poisoning-20241119-p5krpb.html" target="" rel="">The Age</a>. "We're just praying for the family. She's just a loyal, caring sweet person. We value her so much as a friend as well as a colleague." The Department of Foreign Affairs and Trade (DFAT) provided <a href="https://www.9news.com.au/national/laos-methanol-poisoning-melbourne-teens-suspected-methanol-poisoning-identified/b5721fe5-e323-4807-8790-e9d070b51194" target="_blank" rel="noopener">9News</a> with a statement on Wednesday, with a spokesperson saying they were "providing consular assistance" to two Australians and their families in Thailand. "Our thoughts are with them at this deeply distressing time," a spokesperson said. "Owing to our privacy obligations we are unable to provide further comment." Image credits: Facebook

Travel Trouble

From eye exams to blood tests and surgery: how doctors use light to diagnose disease

<div class="theconversation-article-body"><a href="https://theconversation.com/profiles/matthew-griffith-1539353">Matthew Griffith</a>, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> You’re not feeling well. You’ve had a pounding headache all week, dizzy spells and have vomited up your past few meals. You visit your GP to get some answers and sit while they shine a light in your eyes, order a blood test and request some medical imaging. Everything your GP just did relies on light. These are just some of the optical technologies that have had an enormous impact in how we diagnose disease. <h2>1. On-the-spot tests</h2> Point-of-care diagnostics allow doctors to test patients on the spot and get answers in minutes, rather than sending samples to a lab for analysis. The “flashlight” your GP uses to view the inside of your eye (known as an <a href="https://medlineplus.gov/ency/article/003881.htm">ophthalmoscope</a>) is a great example. This allows doctors to detect abnormal blood flow in the eye, deformations of the cornea (the outermost clear layer of the eye), or swollen optical discs (a round section at the back of the eye where the nerve link to the brain begins). Swollen discs are a sign of elevated pressure inside your head (or in the worst case, a brain tumour) that could be <a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/headache/increased-intracranial-pressure-icp-headache">causing your headaches</a>. The invention of <a href="https://openmedscience.com/lighting-the-way-in-healthcare-the-transformative-role-of-lasers-in-medicine/">lasers and LEDs</a> has enabled many other miniaturised technologies to be provided at the bedside or clinic rather than in the lab. <a href="https://theconversation.com/whats-a-pulse-oximeter-should-i-buy-one-to-monitor-covid-at-home-174457">Pulse oximetry</a> is a famous example, where a clip attached to your finger reports how well your blood is oxygenated. It does this by <a href="https://www.howequipmentworks.com/pulse_oximeter/">measuring</a> the different responses of oxygenated and de-oxygenated blood to different colours of light. Pulse oximetry is used at hospitals (and <a href="https://theconversation.com/whats-a-pulse-oximeter-should-i-buy-one-to-monitor-covid-at-home-174457">sometimes at home</a>) to monitor your respiratory and heart health. In hospitals, it is also a valuable tool for detecting <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)60107-X/fulltext">heart defects in babies</a>. <h2>2. Looking at molecules</h2> Now, back to that blood test. Analysing a small amount of your blood can diagnose <a href="https://theconversation.com/blood-tests-and-diagnosing-illness-what-can-blood-tell-us-about-whats-happening-in-our-body-80327">many different diseases</a>. A machine called an automated “full blood count analyser” tests for general markers of your health. This machine directs focused beams of light through blood samples held in small glass tubes. It counts the number of blood cells, determines their specific type, and reports the level of haemoglobin (the protein in red blood cells that distributes oxygen around your body). In minutes, this machine can provide a <a href="https://www.nuffieldhealth.com/article/inside-the-pathology-lab-what-happens-to-my-blood">snapshot</a> of your overall health. For more specific disease markers, blood serum is separated from the heavier cells by spinning in a rotating instrument called a centrifuge. The serum is then exposed to special chemical stains and enzyme assays that change colour depending on whether specific molecules, which may be the sign of a disease, are present. These colour changes can’t be detected with the naked eye. However, a light beam from an instrument called a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476943/#R88">spectrometer</a> can detect tiny amounts of these substances in the blood and determine if the biomarkers for diseases are present, and at what levels. <h2>3. Medical imaging</h2> Let’s re-visit those medical images your GP ordered. The development of fibre-optic technology, made famous for transforming high-speed digital communications (such as the NBN), allows light to get inside the body. The result? High-resolution optical imaging. A common example is an <a href="https://www.medicalnewstoday.com/articles/153737#risks-and-side-effects">endoscope</a>, where fibres with a tiny camera on the end are inserted into the body’s natural openings (such as your mouth or anus) to examine your gut or respiratory tracts. Surgeons can insert the same technology through tiny cuts to view the inside of the body on a video screen during <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553337/">laparoscopic surgery</a> (also known as keyhole surgery) to diagnose and treat disease. <h2>How about the future?</h2> Progress in nanotechnology and a better understanding of the interactions of light with our tissues are leading to new light-based tools to help diagnose disease. These include: <ul> <li> <a href="https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201903441">nanomaterials</a> (materials on an extremely small scale, many thousands of times smaller than the width of a human hair). These are being used in next-generation sensors and new diagnostic tests </li> <li> <a href="https://www.nature.com/articles/s41587-019-0045-y">wearable optical biosensors</a> the size of your fingernail can be included in devices such as watches, contact lenses or finger wraps. These devices allow non-invasive measurements of sweat, tears and saliva, in real time </li> <li> AI tools to analyse how blood serum scatters infrared light. This has allowed researchers to build a <a href="https://www.advancedsciencenews.com/powerful-diagnostic-approach-uses-light-to-detect-virtually-all-forms-of-cancer/">comprehensive database</a> of scatter patterns to detect <a href="https://onlinelibrary.wiley.com/doi/full/10.1002/aisy.202300006">any cancer</a> </li> <li> a type of non-invasive imaging called <a href="https://www.ncbi.nlm.nih.gov/books/NBK554044/">optical coherence tomography</a> for more detailed imaging of the eye, heart and skin </li> <li> fibre optic technology to deliver a tiny microscope into the body on the <a href="https://www.uwa.edu.au/projects/microscope-in-a-needle">tip of a needle</a>. </li> </ul> So the next time you’re at the GP and they perform (or order) some tests, chances are that at least one of those tests depend on light to help diagnose disease.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/231379/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/matthew-griffith-1539353">Matthew Griffith</a>, Associate Professor and ARC Future Fellow and Director, UniSA Microscopy and Microanalysis Facilities, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/from-eye-exams-to-blood-tests-and-surgery-how-doctors-use-light-to-diagnose-disease-231379">original article</a>. </div>

Body

For type 2 diabetes, focusing on when you eat – not what – can help control blood sugar

<div class="theconversation-article-body"> <a href="https://theconversation.com/profiles/evelyn-parr-441878">Evelyn Parr</a>, <a href="https://theconversation.com/institutions/australian-catholic-university-747">Australian Catholic University</a> and <a href="https://theconversation.com/profiles/brooke-devlin-2237174">Brooke Devlin</a>, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a> Type 2 diabetes affects <a href="https://www.aihw.gov.au/reports/diabetes/diabetes/contents/how-common-is-diabetes/type-2-diabetes">1.2 million Australians</a> and accounts for <a href="https://www.diabetesaustralia.com.au/about-diabetes/type-2-diabetes/">85-90%</a> of all diabetes cases. This chronic condition is characterised by high blood glucose (sugar) levels, which carry serious <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30058-2/abstract">health</a> risks. <a href="https://www.nature.com/articles/nrendo.2017.151">Complications</a> include heart disease, kidney failure and vision problems. Diet is an important way people living with type 2 diabetes manage blood glucose, alongside exercise and medication. But while we know individualised, professional dietary advice improves blood glucose, it can be <a href="https://linkinghub.elsevier.com/retrieve/pii/S0168822717317588">complex</a> and is not always <a href="https://www.publish.csiro.au/py/PY13021">accessible</a>. <a href="https://www.sciencedirect.com/science/article/pii/S0168822724008039">Our new study</a> looked at the impact of time-restricted eating – focusing on when you eat, rather than what or how much – on blood glucose levels. We found it had similar results to individualised advice from an accredited practising dietitian. But there were added benefits, because it was simple, achievable, easy to stick to – and motivated people to make other positive changes. <h2>What is time-restricted eating?</h2> Time-restricted eating, also known as <a href="https://www.annualreviews.org/content/journals/10.1146/annurev-nutr-082018-124320">the 16:8 diet</a>, became popular for weight loss around 2015. Studies have since shown it is also an <a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2811116">effective way</a> for people with type 2 diabetes to manage blood glucose. Time-restricted eating involves limiting when you eat each day, rather than focusing on what you eat. You restrict eating to a window during daylight hours, for example between 11am and 7pm, and then fast for the remaining hours. This can sometimes naturally lead to also eating less. Giving your body a break from constantly digesting food in this way helps align eating with natural <a href="https://doi.org/10.1111/jne.12886">circadian rhythms</a>. This <a href="https://doi.org/10.1111/jnc.15246">can help</a> regulate metabolism and improve overall health. For people with type 2 diabetes, there may be specific benefits. They often have their <a href="https://doi.org/10.2337/dc12-2127">highest blood glucose</a> reading in the morning. Delaying breakfast to mid-morning means there is time for physical activity to occur to help reduce glucose levels and prepare the body for the first meal. <h2>How we got here</h2> We ran an <a href="https://www.mdpi.com/2072-6643/12/11/3228">initial study</a> in 2018 to see whether following time-restricted eating was achievable for people with type 2 diabetes. We found participants could easily stick to this eating pattern over four weeks, for an average of five days a week. Importantly, they also had improvements in blood glucose, spending less time with high levels. <a href="https://www.mdpi.com/2072-6643/12/2/505">Our previous research</a> suggests the reduced time between meals may play a role in how the hormone insulin is able to reduce glucose concentrations. <a href="https://doi.org/10.1001/jamanetworkopen.2023.39337">Other studies</a> have confirmed these findings, which have <a href="https://doi.org/10.1186/s12986-021-00613-9">also shown</a> notable improvements in HbA1c. This is a <a href="https://www.ncbi.nlm.nih.gov/books/NBK304271/">marker</a> in the blood that represents concentrations of blood glucose over an average of three months. It is the <a href="https://journals.sagepub.com/doi/10.4137/BMI.S38440">primary clinical tool</a> used for diabetes. However, these studies provided intensive support to participants through weekly or fortnightly meetings with researchers. While we know this level of support <a href="https://www.nature.com/articles/0802295">increases</a> how likely people are to stick to the plan and improves outcomes, it is not readily available to everyday Australians living with type 2 diabetes. <h2>What we did</h2> In our <a href="https://www.sciencedirect.com/science/article/pii/S0168822724008039">new study</a>, we compared time-restricted eating directly with advice from an <a href="https://dietitiansaustralia.org.au/working-dietetics/standards-and-scope/role-accredited-practising-dietitian">accredited practising dietitian</a>, to test whether results were similar across six months. We recruited 52 people with type 2 diabetes who were currently managing their diabetes with up to two oral medications. There were 22 women and 30 men, aged between 35 and 65. Participants were randomly divided into two groups: diet and time-restricted eating. In both groups, participants received four consultations across the first four months. During the next two months they managed diet alone, without consultation, and we continued to measure the impact on blood glucose. In the diet group, consultations focused on changing their diet to control blood glucose, including improving diet quality (for example, eating more vegetables and limiting alcohol). In the time-restricted eating group, advice focused on how to limit eating to a nine-hour window between 10am and 7pm. Over six months, we measured each participant’s blood glucose levels every two months using the HbA1c test. Each fortnight, we also asked participants about their experience of making dietary changes (to what or when they ate). <h2>What we found</h2> We found time-restricted eating was as effective as the diet intervention. Both groups had reduced blood glucose levels, with the greatest improvements occurring after the first two months. Although it wasn’t an objective of the study, some participants in each group also lost weight (5-10kg). When surveyed, participants in the time-restricted eating group said they had adjusted well and were able to follow the restricted eating window. Many told us they had family support and enjoyed earlier mealtimes together. Some also found they slept better. After two months, people in the time-restricted group were looking for more dietary advice to further improve their health. Those in the diet group were less likely to stick to their plan. Despite similar health outcomes, time-restricted eating seems to be a simpler initial approach than making complex dietary changes. <h2>Is time-restricted eating achievable?</h2> The main barriers to following time-restricted eating are social occasions, caring for others and work schedules. These factors may prevent people eating within the window. However, there are many benefits. The message is simple, focusing on when to eat as the main diet change. This may make time-restricted eating more translatable to people from a wider variety of socio-cultural backgrounds, as the types of foods they eat don’t need to change, just the timing. Many people don’t have access to more individualised support from a dietitian, and receive nutrition advice from their GP. This makes time-restricted eating an alternative – and equally effective – strategy for people with type 2 diabetes. People should still try to stick to <a href="https://www.eatforhealth.gov.au/guidelines/guidelines">dietary guidelines</a> and prioritise vegetables, fruit, wholegrains, lean meat and healthy fats. But our study showed time-restricted eating may also serve as stepping stone for people with type 2 diabetes to take control of their health, as people became more interested in making diet and other positive changes. Time-restricted eating might not be appropriate for everyone, especially people on medications which don’t recommend fasting. Before trying this dietary change, it’s best speak to the healthcare professional who helps you manage diabetes.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/241472/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/evelyn-parr-441878">Evelyn Parr</a>, Research Fellow in Exercise Metabolism and Nutrition, Mary MacKillop Institute for Health Research, <a href="https://theconversation.com/institutions/australian-catholic-university-747">Australian Catholic University</a> and <a href="https://theconversation.com/profiles/brooke-devlin-2237174">Brooke Devlin</a>, Lecturer in Nutrition and Dietetics, School of Human Movement and Nutrition Sciences, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/for-type-2-diabetes-focusing-on-when-you-eat-not-what-can-help-control-blood-sugar-241472">original article</a>. </div>

Body

Six people found dead in luxury hotel

A disturbing theory has emerged after six people were found dead in a luxury hotel room in central Bangkok. According to Bangkok’s Metropolitan Police commissioner Thiti Saengsawang, hotel staff at the Grand Hyatt Erawan discovered the bodies of six people in a fifth-floor room after they missed check out time by more than 24 hours. After concluding that the incident did not appear to be a robbery and none of the bodies showed any signs of physical violence, Thai Police are exploring the possibility that the people were poisoned. Police shared that they "needed to find out the motives", and that the deaths were the result of a "killing", not a suicide. Authorities conformed they are investigating the potential poisoning after Thiti said cups with traces of a white powder were located in the room, along with untouched food that had been ordered earlier. As police continue their investigation into the shocking deaths, they are currently searching for a seventh person who was part of the hotel booking and is now a possible suspect. Two of the dead were US citizens of Vietnamese background, while the other four were Vietnamese nationals. Thiti said police believe one member of the group had tried to reach the door to escape but fell and died before they could get there. The Thai government issued a statement after the killings, with Thai Prime Minister Srettha Thavisin saying, "There were no signs of a struggle," adding, "We need to conduct an autopsy." He also "ordered all agencies to urgently take action to avoid impact on tourism,” given that the luxury hotel is situated in a popular tourist area. Image credits: BBC / Royal Thai Police

Travel Trouble

Health retreat responds to woman's suspected mushroom poisoning death

The alternative health centre where Rachael Dixon died after consuming a drink allegedly containing <a href="https://www.oversixty.com.au/health/caring/woman-dies-after-suspected-mushroom-poisoning-at-health-retreat" target="_blank" rel="noopener">poisonous mushrooms</a> have issued a public statement on the incident. The 53-year-old and her friends took part in a holistic wellness retreat at Soul Barn Creative Wellbeing Centre when Dixon fell ill on Saturday night after <span style="background-color: #ffffff; color: #212529; font-family: -apple-system, 'system-ui', 'Segoe UI', Roboto, 'Helvetica Neue', Arial, sans-serif, 'Apple Color Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol', 'Noto Color Emoji'; font-size: 16px;">she allegedly crushed up mushrooms<span style="background-color: #ffffff; color: #212529; font-family: -apple-system, 'system-ui', 'Segoe UI', Roboto, 'Helvetica Neue', Arial, sans-serif, 'Apple Color Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol', 'Noto Color Emoji'; font-size: 16px;"> and consumed them in a drink. While her two friends were rushed to hospital and released a few days later, Dixon went into cardiac arrest, and despite best efforts by paramedics, she died at the scene just after 12am. Soul Barn, a self-described “creative wellbeing centre” specialising in holistic and alternative practices issued a statement on Thursday saying they were devastated by the incident. They also claimed that the event on Saturday that Dixon attended was not run by the centre or facilitated by any of its staff. “Soul Barn hires out workshop (spaces) to external businesses and facilitators,” they said. “The event which took place on April 13 was a private event, and those facilitating the event do not work for or represent Soul Barn in any way. “None of our regular therapists staff or facilitators were present at any point during this event. “We share the shock and devastation of everyone involved, and our hearts are with those families affected.” The health centre will remain closed while police investigate Dixon's death and a report is being prepared for the coroner. Image: 7NEWS

Legal

Woman dies after suspected mushroom poisoning at health retreat

A 53-year-old woman has died and two others have been rushed to hospital after allegedly ingesting poisonous mushrooms while at a holistic wellness retreat. Rachael Dixon became violently ill on Saturday night after she allegedly crushed up mushrooms and consumed them in a drink. Dixon and her two friends were at the Soul Barn Creative Wellbeing Centre, an "alternative health retreat" in Clunes, near Ballarat, when the incident occurred. An ambulance was called after reports she was in cardiac arrest and not breathing, and despite best efforts by paramedics, she died at the scene just after 12am. Her two friend were also rushed to hospital, but were released days later. Police are investigating her sudden death, and are expected to look into if the drink contained 'magic' mushrooms, which contain the hallucinogenic chemical psilocybin. Dixon's son Matthew paid tribute to his mother on Facebook, writing, "To the most loving, most caring person I've ever known can't thank you enough for everything you ever did for me and all the support you gave me." "Words can't begin to describe how much I will miss you, wish I could give you one last hug." Soul Barn has remained closed since the incident as local business owners and residents said the incident was "confronting" and "devastating". The death comes after Victorian authorities warned residents earlier this month that poisonous mushrooms were growing across the state. “Unless you are an expert, do not pick and eat wild mushrooms in Victoria,” acting chief health officer Evelyn Wong said. “There is no home test available to distinguish safe and edible mushrooms from poisonous mushrooms.” Image credits: Facebook

Caring

Centenarian blood tests give hints of the secrets to longevity

<a href="https://theconversation.com/profiles/karin-modig-1473484">Karin Modig</a>, <a href="https://theconversation.com/institutions/karolinska-institutet-1250">Karolinska Institutet</a> Centenarians, once considered rare, have become commonplace. Indeed, they are the <a href="https://www.weforum.org/agenda/2021/02/living-to-one-hundred-life-expectancy/">fastest-growing demographic group</a> of the world’s population, with numbers roughly doubling every ten years since the 1970s. How long humans can live, and what determines a long and healthy life, have been of interest for as long as we know. Plato and Aristotle discussed and <a href="https://pubmed.ncbi.nlm.nih.gov/12092789/">wrote about the ageing process</a> over 2,300 years ago. The pursuit of understanding the secrets behind exceptional longevity isn’t easy, however. It involves <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105197/">unravelling the complex interplay</a> of genetic predisposition and lifestyle factors and how they interact throughout a person’s life. Now our recent study, <a href="https://link.springer.com/article/10.1007/s11357-023-00936-w">published in GeroScience</a>, has unveiled some common biomarkers, including levels of cholesterol and glucose, in people who live past 90. Nonagenarians and centenarians have long been of intense interest to scientists as they may help us understand how to live longer, and perhaps also how to age in better health. So far, studies of centenarians have often been small scale and focused on a selected group, for example, excluding centenarians who live in care homes. <h2>Huge dataset</h2> Ours is the largest study comparing biomarker profiles measured throughout life among exceptionally long-lived people and their shorter-lived peers to date. We compared the biomarker profiles of people who went on to live past the age of 100, and their shorter-lived peers, and investigated the link between the profiles and the chance of becoming a centenarian. Our research included data from 44,000 Swedes who underwent health assessments at ages 64-99 - they were a sample of <a href="https://pubmed.ncbi.nlm.nih.gov/28158674/">the so-called Amoris cohort</a>. These participants were then followed through Swedish register data for up to 35 years. Of these people, 1,224, or 2.7%, lived to be 100 years old. The vast majority (85%) of the centenarians were female. Twelve blood-based biomarkers related to inflammation, metabolism, liver and kidney function, as well as potential malnutrition and anaemia, were included. All of these <a href="https://www.nature.com/articles/s41591-019-0719-5">have been associated</a> with ageing or mortality in previous studies. The biomarker related to inflammation was uric acid – a waste product in the body caused by the digestion of certain foods. We also looked at markers linked to metabolic status and function including total cholesterol and glucose, and ones related to liver function, such as alanine aminotransferase (Alat), aspartate aminotransferase (Asat), albumin, gamma-glutamyl transferase (GGT), alkaline phosphatase (Alp) and lactate dehydrogenase (LD). We also looked at creatinine, which is linked to kidney function, and iron and total iron-binding capacity (TIBC), which is linked to anaemia. Finally, we also investigated albumin, a biomarker associated with nutrition. <h2>Findings</h2> We found that, on the whole, those who made it to their hundredth birthday tended to have lower levels of glucose, creatinine and uric acid from their sixties onwards. Although the median values didn’t differ significantly between centenarians and non-centenarians for most biomarkers, centenarians seldom displayed extremely high or low values. For example, very few of the centenarians had a glucose level above 6.5 earlier in life, or a creatinine level above 125. For many of the biomarkers, both centenarians and non-centenarians had values outside of the range considered normal in clinical guidelines. This is probably because these guidelines are set based on a younger and healthier population. When exploring which biomarkers were linked to the likelihood of reaching 100, we found that all but two (alat and albumin) of the 12 biomarkers showed a connection to the likelihood of turning 100. This was even after accounting for age, sex and disease burden. The people in the lowest out of five groups for levels of total cholesterol and iron had a lower chance of reaching 100 years as compared to those with higher levels. Meanwhile, people with higher levels of glucose, creatinine, uric acid and markers for liver function also decreased the chance of becoming a centenarian. In absolute terms, the differences were rather small for some of the biomarkers, while for others the differences were somewhat more substantial. For uric acid, for instance, the absolute difference was 2.5 percentage points. This means that people in the group with the lowest uric acid had a 4% chance of turning 100 while in the group with the highest uric acid levels only 1.5% made it to age 100. Even if the differences we discovered were overall rather small, they suggest a potential link between metabolic health, nutrition and exceptional longevity. The study, however, does not allow any conclusions about which lifestyle factors or genes are responsible for the biomarker values. However, it is reasonable to think that factors such as nutrition and alcohol intake play a role. Keeping track of your kidney and liver values, as well as glucose and uric acid as you get older, is probably not a bad idea. That said, chance probably plays a role at some point in reaching an exceptional age. But the fact that differences in biomarkers could be observed a long time before death suggests that genes and lifestyle may also play a role.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/215166/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/karin-modig-1473484">Karin Modig</a>, Associate Professor, Epidemiology, <a href="https://theconversation.com/institutions/karolinska-institutet-1250">Karolinska Institutet</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/centenarian-blood-tests-give-hints-of-the-secrets-to-longevity-215166">original article</a>.

Retirement Life

Deadly mushroom lunch survivor speaks out for the first time

The man who survived the deadly mushroom lunch in Victoria last year has spoken out for the first time, sharing what has kept him going through the tragedy. Pastor Ian Wilkinson, 70, was hospitalised for ingesting the poison, which claimed the lives of his wife Heather, his brother Don and his sister-in-law Gail, after attending lunch at Erin Patterson's home on July 29th 2023. Ms Patterson has since been charged with three counts of murder and five of attempted murder after inviting her ex-husband’s family over to her home for lunch and allegedly serving them the poisoned dish. Six months on, Ian Wilkinson addressed his congregation as he returned to the Korumburra Baptist Church on Sunday for the first time since the alleged poisoning, saying it had been a “big week” full of milestones for him. “At the start of the week it was six months since Heather, Gail and Don went to be with the Lord …” he told the congregation. “Friday was my birthday and yesterday was our 45th wedding anniversary." “So it’s been a pretty big week but I am grateful for all that God has given me, God has done through me.” The week prior marked 25 years since he first took on the role of pastor of the Korumburra parish, with the parishioners offering him a small gift following the sermon. Mr Wilkinson seemed overcome with emotion during parts his sermon, sharing with the congregation that he was grateful to be back after a terrifying two-month stint in the hospital while he fought for his life after the poisoning. “The ways are sometimes hard but God is good. He’s with us,” he said. “He promised to never leave … and I can say, that is true.” Image credits: Supplied

Caring

8 reasons everyone should know their blood type

Why you should know your blood type What’s in a blood type? Potentially a lot, according to research, including a review of studies published in the Wiley Interdisciplinary Reviews: Systems Biology and Medicine, that connects different blood groups to everything from risk of heart disease and dementia to urinary tract infections and the norovirus. While none of the studies are conclusive about cause and effect (they can’t say X blood type causes Y disease) and any increased risks are still pretty small, the research does highlight the importance of knowing your type – A, B, AB, or O – and how it could affect your wellbeing. Blood clots: Type AB, A, and B increases risk Danish researchers studied how blood type interacts with a genetic predisposition for deep-vein thrombosis (DVT), or blood clots in the lower legs that can travel to the lungs and become life-threatening. After analysing data on about 66,000 people over more than 30 years, they found that those with type AB, A, or B had a 40 per cent higher risk of DVT than people with type O, the most common type. When the scientists did further analysis to see which factors have the biggest impact on DVT risk on a population level, they found that an AB blood type contributed to about 20 per cent of blood clots; genetic mutations accounted for 11 per cent, being overweight accounted for 16 per cent, and smoking accounted for six per cent. Heart disease: Type AB, B, and A all increase risk People whose blood type is A, B, or AB have an increased risk of heart disease and shorter life spans than people who have type O blood, according to a large study published in BMC Medicine. After following more than 50,000 middle-age and elderly people for seven years, on average, researchers found that as many as nine per cent of cardiovascular deaths were attributed to having non-O blood types. However, as any doctor will tell you, lifestyle factors like weight, smoking and diet, which, unlike blood type, are modifiable, have a much greater impact on heart disease. Stomach cancer: Types A and AB increases risk Researchers have known for a while that people with blood type A are at risk for stomach cancer. But research published in BMC Cancer shows that people with blood type AB are also at risk. Using genetic data from a large number of cases and controls, researchers found a link between both blood types and gastric cancer in Chinese populations. A review of 39 previous studies confirmed their findings. Fertility: Type O reduces it Women with this blood type were twice as likely to have blood levels of the hormone FSH high enough to indicate low ovarian reserve, a measure of fertility, according to a study published in Human Reproduction. Researchers couldn’t say for sure why, though. Given that type O blood is the most prevalent, it doesn’t pay to worry too much about it. Age is a far more important risk factor for fertility problems. Pregnancy risks This has nothing to do with your “letter” blood type or the type determined by the ABO grouping system. This has to do with what’s known as the Rhesus (Rh) factor, which determines whether your blood type is positive or negative. This could cause complications in pregnant women if the baby’s Rh blood type is different from the mother’s. For instance, if the mother has a negative blood type and the baby has a positive one, the mother’s body can actually build up antibodies against the baby’s blood type. Luckily, this doesn’t affect the baby, but it could have a negative effect on future pregnancies. Fortunately, doctors can give pregnant women a shot early in their pregnancy that can prevent Rh-incompatibility problems. Dementia and memory loss: Type AB increases risk People with type AB blood have an 82 per cent greater risk for cognitive decline later in life, according to a study published in Neurology. That’s likely because they have larger amounts of what’s known as the Factor VIII protein, which helps with blood clotting. Study participants with higher levels of this protein were 24 per cent more likely to develop memory problems – regardless of their blood type – than people with lower levels. Blood type, however, is far from the only, or even most important, factor that affects your risk for cognitive decline. Stroke: Type O has the lowest risk People with a blood type other than O (the most common) have a higher risk of cardiovascular issues such as stroke, according to a study published in the Journal of Thrombosis and Haemostasis. Biologists are still investigating why this might be; one possible explanation is that non-O blood types contain more of the Von Willebrand factor, a protein that has been connected to blood clotting and stroke in the past. Mosquitos like Type O blood If you find yourself scratching bug bites all summer long, your blood type might be to blame. In a one small study, researchers found that type Os are up to twice as attractive to mosquitoes as type As, with type Bs falling somewhere in the middle. Image credits: Shutterstock This article originally appeared on <a href="https://www.readersdigest.com.au/healthsmart/8-reasons-everyone-should-know-their-blood-type" target="_blank" rel="noopener">Reader's Digest</a>.

Body

"I've lost complete blood flow": Robert Irwin's near miss with python

Young wildlife warrior Robert Irwin suffered a near miss during a rescue mission over the weekend, when he tried to relocate a carpet python off the road. The 19-year-old took to Instagram on Sunday to share a video of him almost getting bit by the wild snake. "Gee, that gets the heart rate up - he missed me by that much," he said when the snake struck at him. "He's grumpy... he's really keen on biting me... what a gorgeous snake, he's big, he's not venomous but... they're designed to constrict," he said as the python began wrapping its body around his arm to ''constrict" him. "He's got a good grip there, I've lost complete blood flow to my hand, it's completely blue.. and I have no feeling left in my hand," he added. He eventually managed to rescue the snake, and relocated it to a safe spot in the bush the day after. "Near miss! Definitely had a good laugh with this grumpy carpet python - but great to get him rescued off the road and relocated to a much safer spot!" he captioned the post. <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/reel/C0Fc3k-hiy9/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/C0Fc3k-hiy9/?utm_source=ig_embed&utm_campaign=loading" target="_blank" rel="noopener">A post shared by Robert Irwin (@robertirwinphotography)</a> </div> </blockquote> Fans shared their shock and couldn't help but comment on how much the young conservationist was like his late father, Steve Irwin. "Dude you are killing us with these like-father-like-son bits," one fan wrote. "Holy crap. I actually thought I was watching Steve for a second and it took me back a moment. He's very much still alive in his family. No doubt about that," another added. "This is precarious yet hiss-terical !😂 all at the same time. Thank you for helping snakey dude slither to safety! 👍🏼💕" added a fellow conservationist. Images: Instagram

Travel Trouble

Worried about getting a blood test? 5 tips to make them easier (and still accurate)

<a href="https://theconversation.com/profiles/sapha-shibeeb-1481231">Sapha Shibeeb</a>, <a href="https://theconversation.com/institutions/rmit-university-1063">RMIT University</a> Blood tests are a common medical procedure, offering valuable insights into a person’s health. Whether you’re getting a routine check-up, diagnosing a medical condition or monitoring treatment progress, understanding the process can make the experience more comfortable and effective. For the majority of patients, blood collections are a minor inconvenience. Others may feel <a href="https://www.sciencedirect.com/science/article/abs/pii/S0887618506000041">uneasy and anxious</a>. Preparation strategies can help get you through the procedure. <h2>How blood is collected</h2> During venipuncture (blood draw), the phlebotomist (blood collector) inserts a needle through the skin into a vein and a small amount of blood is collected and transferred into a test tube. Tubes are sent to a laboratory, where the blood is analysed. A laboratory technician may count or examine cells and measure the levels of minerals/salts, enzymes, proteins or other substances in the sample. For some tests, blood plasma is separated out by spinning (centrifuging) the sample. Others pass a light beam through the sample to determine the amount of a chemical present. For collection, the phlebotomist usually selects a vein in the crook of your elbow, where veins are readily accessible. Blood can also be drawn from veins in the wrists, fingers or heels. A tourniquet may be applied to restrict blood flow and make the chosen vein puff out. <h2>Different tests require different preparation</h2> Before a blood test, the GP or health-care provider will give you specific instructions. These may include fasting for up to 12 hours or temporarily discontinuing certain medications. It is crucial to follow these guidelines meticulously as they can significantly impact the accuracy of your test results. For example, fasting is required before glucose (blood sugar) and lipids (blood fats) testing because blood sugar and cholesterol levels typically increase after a meal. If the blood test requires fasting, you will be asked not to eat or drink (no tea, coffee, juice or alcohol) for about eight to 12 hours. Water is allowed but smoking should be avoided because it can increase <a href="https://diabetesjournals.org/care/article/19/2/112/19825/Acute-Effect-of-Cigarette-Smoking-on-Glucose">blood sugar, cholesterol and triglyceride levels</a>. Generally, you will be asked to fast overnight and have the blood collection done in the morning. Fasting for longer than 15 hours could impact your results, too, by causing dehydration or the release of certain chemicals in the blood. If you have diabetes, you must consult your doctor prior to fasting because it can increase the risk of hypoglycemia (low blood sugar) in people with type 1 diabetes. Most type 2 diabetics can safely fast before a blood test but there are some exceptions, such as people who are taking certain medications including insulin. <h2>5 tips for a better blood test</h2> To improve your blood collection experience, consider these tips: 1. Hydrate Drink plenty of water right up to 30 minutes before your appointment. Adequate hydration improves blood flow, making your veins more accessible. Avoid <a href="https://academic.oup.com/labmed/article/34/10/736/2657269">strenuous exercise</a> before your blood test, which can increase some blood parameters (such as liver function) while decreasing others (such as sodium). 2. Loose clothing Wear clothing that allows easy access to your arms to ensure a less stressful procedure. 3. Manage anxiety If the sight of blood or the procedure makes you anxious, look away while the needle is inserted and try to keep breathing normally. Distraction can help – virtual reality has been <a href="https://pubmed.ncbi.nlm.nih.gov/31889358/">trialled</a> to reduce needle anxiety in children. You could try bringing something to read or music to listen to. 4. Know your risk of fainting If you’re prone to fainting, make sure to inform the phlebotomist when you arrive. You can have your blood drawn while lying down to minimise the risk of passing out and injury. Hydration helps maintain blood pressure and can also <a href="https://www.ahajournals.org/doi/10.1161/01.CIR.0000101966.24899.CB">reduce the risk</a> of fainting. 5. Discuss difficult veins Some people have smaller or scarred veins, often due to repeated punctures, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989034/">chemotherapy</a> or blood thinner use. In such cases, venipuncture may require multiple attempts. It is important to talk to the phlebotomist if you feel discomfort or significant pain. A finger prick can be performed as an alternative for some tests, such as blood glucose levels. But other comprehensive tests require larger blood volume. <h2>Blood draws after lymph node removal</h2> Historically, there were concerns about drawing blood from an arm that had undergone lymph node removal. This was due to the risk of <a href="https://www.cancer.gov/about-cancer/treatment/side-effects/lymphedema/lymphedema-pdq#:%7E:text=Lymphedema%20is%20the%20build%2Dup,the%20way%20that%20it%20should.">lymphedema</a>, a condition marked by fluid build-up in the affected arm. Lymph nodes may have been removed (<a href="https://www.ncbi.nlm.nih.gov/books/NBK564397/#:%7E:text=Lymph%20node%20dissection%2C%20also%20known,surgical%20management%20of%20malignant%20tumors.">lymphadenectomy</a>) for cancer diagnosis or treatment. However, a <a href="https://ascopubs.org/doi/10.1200/JCO.2015.61.5948">2016 study</a> showed people who’ve had lymph nodes removed are not at a higher risk of developing lymphedema following blood draws, even when drawing blood from the affected arm. <h2>After your blood test</h2> The whole blood test procedure usually lasts no more than a few minutes. Afterwards, you may be asked to apply gentle pressure over a clean dressing to aid clotting and reduce swelling. If you do experience swelling, bruising or pain after a test, follow general first aid procedures to alleviate discomfort. These include applying ice to the site, resting the affected arm and, if needed, taking a pain killer. It is usually recommended you do not do heavy lifting for a few hours after a blood draw. This is to prevent surges in blood flow that could prevent clotting where the blood was taken.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/216073/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/sapha-shibeeb-1481231">Sapha Shibeeb</a>, Senior lecturer in Laboratory Medicine , <a href="https://theconversation.com/institutions/rmit-university-1063">RMIT University</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/worried-about-getting-a-blood-test-5-tips-to-make-them-easier-and-still-accurate-216073">original article</a>.

Body

Past charges against mushroom poisoning suspect uncovered

Erin Patterson, the woman under investigation for allegedly cooking the deadly mushroom meal that claimed the lives of three people, has previously faced a series of charges after being involved in a drunk-driving incident. According to reports from The Australian, the 49-year-old was convicted in 2004 of driving drunk in an unregistered vehicle. Court records have revealed that Patterson, who was then known as Erin Trudi Scutter and was aged 29, faced legal consequences for her reckless actions, losing her license for 30 months after crashing her vehicle in the eastern suburbs of Melbourne while heavily intoxicated. The reports revealed that after the crash, she fled from authorities by speeding away from the crash scene, reaching 95 km/h in a 60 km/h zone. The convictions that were handed down were for charges of failing to stop a vehicle after an accident, failing to provide identifying information after causing property damage, using an unregistered vehicle on a highway, failing to provide information after property damage, and driving at 95 km/h in a restricted 60 km/h zone. At the time of the crash, Erin's blood alcohol level was 0.14 per cent, indicating significant impairment, however the charges of drink driving were dropped, potentially due to overlapping elements in other charges. Patterson has yet to comment on the previous charges, after being advised by her lawyer not to make any public comments as she remains under investigation for the deadly mushroom meal. She has <a href="https://www.oversixty.com.au/finance/legal/details-of-erin-patterson-s-police-statement-around-fatal-mushroom-meal-revealed" target="_blank" rel="noopener">denied any wrongdoing</a> in the mushroom incident, although according to police, they are investigating Patterson because she was the only adult among five who did not either die or suffer severe illness after ingesting the deadly mushrooms. Image credits: A Current Affair

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New details emerge in fatal mushroom poisoning incident

The former spouse of the Victorian woman responsible for preparing a meal for three individuals who tragically passed away, was placed in a medically induced coma last year following an unexpected severe digestive ailment. The revelation surfaces as <a href="https://www.theage.com.au/national/victoria/forensic-tests-on-food-dehydrator-found-at-tip-after-mushroom-deaths-20230808-p5dusv.html" target="_blank" rel="noopener">The Age Newspaper reports</a> that law enforcement have carried out forensic testing on a dehydrator found at a waste disposal site near Erin Patterson's home in Leongatha, southeast of Melbourne. Investigators are now exploring whether this apparatus was utilised to preserve the mushrooms before being discarded. The Age has additionally gained access to Erin's ex-husband Simon's social media posts, in which he recounts a mysterious severe gastrointestinal illness that nearly claimed his life. "I collapsed at home and subsequently spent 16 days in an induced coma, undergoing three emergency surgeries mainly targeting my small intestine, along with another planned surgical procedure," he wrote. "My family was summoned twice to bid me farewell as my chances of survival were minimal." Within the same social media post, he extended gratitude to Ms. Patterson for her support. Despite their separation, the two maintain an amicable relationship. Patterson, aged 48, cooked the fateful lunch which law enforcement suspect might have contained death cap mushrooms. The mother of two is now under police scrutiny after the demise of her ex-husband Simon Patterson's parents, Gail and Don Patterson, as well as Gail's sister Heather Wilkinson. Heather's husband, Ian, is currently in critical condition at Melbourne's Austin Hospital and is awaiting a liver transplant. All four individuals exhibited symptoms consistent with death cap mushroom poisoning following the lunch, which occurred on July 29. Ms Patterson has consistently <a href="https://www.oversixty.com.au/finance/legal/i-didn-t-do-anything-i-love-them-woman-who-cooked-meal-with-deadly-mushrooms-speaks-out" target="_blank" rel="noopener">maintained her innocence</a>, expressing that she held strong affection for her in-laws, particularly considering Gail's role as a motherly figure. Police have also characterised the case as intricate and potentially devoid of malicious intent. Death cap mushrooms possess the potential to cause grave damage to the liver and kidneys, leading to fatality. Symptoms include abdominal discomfort vomiting, and nausea, yet much of the harm can transpire before symptoms surface. Ms Patterson herself remained unaffected by the luncheon she organised, and her two children have been taken into protective custody as a preventive measure, according to police statements. Detective Inspector Dean Thomas of the Homicide Squad indicated that authorities are yet to determine whether they are dealing with a potential crime or an unfortunate accident. Images: Facebook / A Current Affair

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"I didn't do anything. I love them": Woman who cooked meal with deadly mushrooms speaks out

A Victorian woman who cooked the meal that resulted in the suspected mushroom poisoning, which left three elderly family members dead and one fighting for his life has tearfully broken her silence. Erin Patterson, 48, served the lunch to four people at Leongatha on July 29, including her former in-laws Don and Gail Patterson, who after falling sick later that evening, passed away from symptoms consistent with death cap mushroom poisoning. Gail's sister Heather Wilkinson also passed away, with Heather’s husband, Ian in a critical condition at Melbourne’s Austin Hospital after suffering from the suspected poisoning. "I didn't do anything. I love them," Erin told A Current Affair. A clearly distraught Erin confused Don for Ian, who is currently being treated for his symptoms. "I'm devastated that they're gone and I hope with every fibre of my being that Don pulls through." “I’m so devastated by what’s happened, by the loss of Don, Don is still in hospital, by the loss of Ian and Heather and Gail," she repeated. “They were some of the best people I’ve ever met. “Gail was like the mum I didn’t have because my mum passed away four years ago, Gail had never been anything but good and kind to me,” she added. “Ian and Heather were some of the best people I’d ever met. They never did anything wrong to me. “I’m so devastated about what’s happened and the loss to the community and to the families and to my own children. They've lost their grandmother," she said, and added that she felt "so sorry" that they lost their lives. Erin was interviewed by police and later on released. Officials had also removed her two children from her care as a “precaution”. Homicide Squad Detective Inspector Dean Thomas also added that police are still determining whether this was an accident or a crime. “We’re working to determine what has gone on, to see if there is any nefarious activity that has occurred or if it was accidental.” “We have to keep an open mind,” he said. Police were also still unsure where the mushrooms were sourced from, and that it was a "complex case". Image: A Current Affair

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No, you can’t reverse ageing by injecting ‘young blood’ and fasting. But that doesn’t stop people trying

<a href="https://theconversation.com/profiles/rachael-jefferson-buchanan-297850">Rachael Jefferson-Buchanan</a>, <a href="https://theconversation.com/institutions/charles-sturt-university-849">Charles Sturt University</a> Like many celebrities and entrepreneurs, 45-year-old US tech billionaire Bryan Johnson is <a href="https://www.smh.com.au/lifestyle/health-and-wellness/taking-the-blood-of-your-17-year-old-son-anti-ageing-has-gone-too-far-20230530-p5dcd6.html">trying to reverse the ageing process</a>. Spending an average of US$2 million a year on an anti-ageing regimen, Johnson <a href="https://medium.com/future-literacy/at-45-i-now-age-slower-than-the-average-10-year-old-6932448fc608">claims</a> he now ages slower than some children. He explains: “the pace my body accumulates ageing damage is less than the average ten year old”. Many of Johnson’s age-reversal methods are questionable, involve dodgy science, and have known side effects. While you can’t stop the ageing process, and the gradual decline our bodies experience as we advance in years, there are some things we can all do – for free – to maintain our health as we age. <h2>What does Johnson do? And is it scientific?</h2> Fasting Johnson reports fasting for 23 hours a day. He then eats <a href="https://medium.com/future-literacy/one-meal-23-hr-fast-100-nutrition-18187a2f5b">one meal a day</a>: 2,250 calories of nutrient-dense food “customised” to his body’s needs. Eating for time-restricted periods in the day can have a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650338/">positive effect</a> on how we <a href="https://pubmed.ncbi.nlm.nih.gov/29955217/">metabolise nutrients</a>, inflammation levels, hormonal regulation, and <a href="https://www.health.harvard.edu/blog/how-good-is-your-cardiometabolic-health-and-what-is-that-anyway-202208182803">cardiometabolic health</a> (blood sugar, <a href="https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/triglycerides/art-20048186">triglycerides</a>, cholesterol, blood pressure, BMI and waist circumference). However, a Spartan-like food intake can <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121099/">impair</a> how our body responds to sugar (known as glucose tolerance). And it’s not necessarily any more effective for weight maintenance than <a href="https://pubmed.ncbi.nlm.nih.gov/29419624/">reducing calorie intake at each meal</a>. Large-scale, long-term human trials are needed to confirm the <a href="https://pubmed.ncbi.nlm.nih.gov/34728336/">limited risk-benefit</a> findings of fasting. Acid peels Johnson has weekly <a href="https://www.asds.net/skin-experts/skin-treatments/chemical-peels/chemical-peels-for-aging-skin">acid peels</a> (which use a mild acid to exfoliate the skin) to maintain a “youthful glow”. But you cannot smooth sagging facial skin or remove deep scars or wrinkles. Acid peels also <a href="https://www.mayoclinic.org/tests-procedures/chemical-peel/about/pac-20393473">come with risks</a>, including organ damage, infection, scarring and swelling. Plasma infusions Perhaps the most bizarre youth-inducing procedure Johnson has attempted is receiving blood transfusions from his 17-year-old son. US biotech companies have explored <a href="https://www.theguardian.com/society/2020/feb/02/could-young-blood-stop-us-getting-old-transfusions-experiments-mice-plasma">plasma infusions</a> to tackle age-related diseases in humans for decades. But there are no proven clinical benefits. <a href="https://www.redcrossblood.org/donate-blood/blood-donation-process/what-happens-to-donated-blood/blood-transfusions/risks-complications.html">Side effects from blood transfusions</a> include blood-borne infections, fever and allergic reactions. <h2>Historical attempts to stay youthful</h2> Humans have been experimenting with <a href="https://academic.oup.com/biomedgerontology/article/59/6/B515/662071">anti-ageing methods for centuries</a>. These have included all sorts of behavioural and lifestyle practices that are quirky, questionable, and even sadistic. Ancient practices included <a href="https://www.marieclaire.com/beauty/news/a14382/anti-aging-beauty-through-history/">crocodile dung face masks</a>, which the Greeks and Romans used to brighten their complexions. Romans also used <a href="https://beautytap.com/2019/03/donkey-milk">donkey milk</a> and <a href="https://www.ancient-origins.net/history/swans-fat-crocodile-dung-and-ashes-snails-achieving-beauty-ancient-rome-003240">swan fat</a> to minimise wrinkles, due to their acclaimed rejuvenating properties. <a href="https://www.livescience.com/44071-cleopatra-biography.html">Cleopatra</a> apparently took daily baths in sour donkey milk. To sustain this lavish habit, she had a <a href="https://www.naturanecosmetics.com/en/content/26-faits-historiques">herd of 700 donkeys</a>. Sour milk contains <a href="https://science.jrank.org/pages/3780/Lactic-Acid-Lactic-acid-in-foods.html">lactic acid</a>, a naturally occurring <a href="https://www.mecca.com.au/edits/ingredients/alpha-hydroxy-acids/">alpha-hydroxy acid (AHA)</a> that exists in many modern-day exfoliants. So this idea was grounded in basic science, at least. <figure class="align-center "><img src="https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=754&fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=600&h=400&fit=crop&dpr=1 600w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=30&auto=format&w=600&h=400&fit=crop&dpr=2 1200w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=15&auto=format&w=600&h=400&fit=crop&dpr=3 1800w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=754&h=503&fit=crop&dpr=1 754w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=30&auto=format&w=754&h=503&fit=crop&dpr=2 1508w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&q=15&auto=format&w=754&h=503&fit=crop&dpr=3 2262w" alt="Milk bath with dried fruits and flowers" /><figcaption>Don’t waste milk on a bath. <a class="source" href="https://www.shutterstock.com/image-photo/bath-milk-flowers-1051210370">Shutterstock</a></figcaption></figure> During the 16th and 17th century, “Countess Dracula” aka <a href="https://en.wikipedia.org/wiki/Elizabeth_B%C3%A1thory">Elizabeth Bathory</a> allegedly resorted to serial killing to quench her thirst for youthfulness, <a href="https://www.nationalgeographic.com/travel/article/the-bloody-legend-of-hungarys-serial-killer-countess">bathing in the blood of her young victims</a>. <h2>The quest continues with cryotherapy</h2> Fountain of youth fixations have inspired many contemporary anti-ageing trends. Exposure to cold is a firm favourite. <a href="https://www.nature.com/articles/s43587-023-00383-4">Some research</a> suggests this could have <a href="https://neurosciencenews.com/cold-aging-22928/">benefits</a> relating to longevity, by slowing cellular degeneration, <a href="https://www.cryo.com.au/anti-ageing-benefits-of-whole-body-cryotherapy/">stimulating collagen and elastin production</a>, increasing the metabolism, and reducing inflammation. Dutch motivational speaker Wim Hof includes <a href="https://www.wimhofmethod.com/cold-water-immersion">cold water immersion</a> as one of the three pillars of his <a href="https://www.wimhofmethod.com/">Wim Hof Method</a> to “increase mind-body connection”. Athletes such as <a href="https://www.dailymail.co.uk/sport/football/article-2469985/Cristiano-Ronaldo-buys-Cryotherapy-chamber.html">Cristiano Ronaldo</a> use <a href="https://my.clevelandclinic.org/health/treatments/21099-cryotherapy">cryotherapy</a>, exposing their bodies to extremely cold temperatures for two to four minutes to decrease the signs of ageing and enhance their general health. However, the <a href="https://www.medicinenet.com/what_are_the_side_effects_of_cryotherapy/article.htm">risks of cryotherapy</a> include bone fractures, frostbite, nerve damage, bleeding, cramping, swelling and skin infections. <h2>So what can we do to age well?</h2> Two of the more mainstream anti-ageing methods that Johnson recommends are the daily self-care habits of sleep and exercise. He has a <a href="https://medium.com/future-literacy/sleep-and-impulse-control-87e844218ff2">strict sleep schedule</a> that involves retiring to bed at 8pm, with a one-hour wind-down in a darkened room. Adults report poorer sleep quality and difficulty being able to sleep for long enough <a href="https://www.news-medical.net/health/How-Does-the-Suprachiasmatic-Nucleus-(SCN)-Control-Circadian-Rhythm.aspx">as they age</a>. Sleeping too much or too little is <a href="https://www.frontiersin.org/articles/10.3389/fpubh.2023.1043347/full">associated with</a> a greater risk of obesity, heart disease and <a href="https://theconversation.com/research-check-can-sleeping-too-much-lead-to-an-early-death-101323">premature death</a>. Developing a regular sleep routine, reducing bedroom distractions such as mobile phones, and exercising regularly can all help to <a href="https://www.sleepfoundation.org/aging-and-sleep">alleviate sleep problems</a>. <figure class="align-center "><img src="https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=754&fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=600&h=383&fit=crop&dpr=1 600w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=30&auto=format&w=600&h=383&fit=crop&dpr=2 1200w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=15&auto=format&w=600&h=383&fit=crop&dpr=3 1800w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=754&h=482&fit=crop&dpr=1 754w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=30&auto=format&w=754&h=482&fit=crop&dpr=2 1508w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&q=15&auto=format&w=754&h=482&fit=crop&dpr=3 2262w" alt="Child and grandfather walk on a beach" /><figcaption>Exercise is also important for healthy ageing. <a class="source" href="https://unsplash.com/photos/s-vhziQHngM">Vidar Nordi Mathisen/Unsplash</a></figcaption></figure> Exercise, often cited as a <a href="https://www.marketwatch.com/story/exercise-is-the-wonder-drug-for-healthy-aging-11633642719">wonder drug for healthy ageing</a>, is something Johnson takes very seriously. He does a “<a href="https://www.youtube.com/watch?v=HNywRJgCRaQ">Blueprint</a>” workout that includes specially designed daily techniques, as well as <a href="https://www.hsph.harvard.edu/nutritionsource/high-intensity-interval-training/">high-intensity interval training sessions</a>, hiking and playing sport. From middle age onwards, we all need to exercise regularly, to increase our muscle mass, bone density, strength, endurance, coordination and balance. One of the greatest health risks for older people is <a href="https://www.ncbi.nlm.nih.gov/books/NBK560761/">falling</a>, which balance, flexibility, endurance and strength training <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC381224/">can help</a> reduce. Physical activity can bring <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408452/">social benefits</a> in older adults if undertaken in groups, and there are well-known <a href="https://www.whiddon.com.au/yourlife/the-mental-health-benefits-of-exercise-for-older-adults/">mental health gains</a>. Small changes in sleep, diet (eating <a href="https://health.gov/news/202107/nutrition-we-age-healthy-eating-dietary-guidelines">plenty of vegetables, fruit, wholegrains, healthy fats, and enough protein</a>), and exercise can support <a href="https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-020-01900-5">healthy ageing</a>, reducing the chance of early death, and helping us all to lead an active and independent life in our senior years. Now that is something worth investing in.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/207038/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/rachael-jefferson-buchanan-297850">Rachael Jefferson-Buchanan</a>, Lecturer in Human Movement Studies (Health and PE) and Creative Arts, <a href="https://theconversation.com/institutions/charles-sturt-university-849">Charles Sturt University</a> This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/no-you-cant-reverse-ageing-by-injecting-young-blood-and-fasting-but-that-doesnt-stop-people-trying-207038">original article</a>. Images: Getty

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6 things a food poisoning expert would never eat

If you want to know how to avoid food poisoning, you better listen to food poisoning expert and lawyer Bill Marler. He’s a products liability and personal injury attorney specialising in food-borne illnesses as well as the managing partner of Marler Clark, dubbed “The Food Safety Law Firm”. With twenty years in the industry, he’s won more than $600 million in compensation claims for his clients since 1998. In an article posted in the <a href="http://www.foodpoisonjournal.com/food-poisoning-information/six-foods-bill-marler-never-eats/#.VrJ3Kvl96uV" target="_blank" rel="noopener">Food Poisoning Journal</a>, Bill has revealed the six foods he refused to eat. Unpasteurised (“raw”) milk and packaged juices Unpasteurised milk, sometimes called “raw” milk, can be contaminated with bacteria, viruses and parasites. Between 1998 and 2011, there were 148 food poisoning outbreaks linked to raw milk and raw milk products in the US—and keep in mind that comparatively few people in the country ever consume these products, so 148 outbreaks is nothing to ignore. As for unpasteurised packaged juices, one of Marler’s earliest cases was the 1996 E. coli outbreak from unpasteurised Odwalla apple juice. As a result, he won’t go near raw milk or juice. “There’s no benefit big enough to take away the risk of drinking products that can be made safe by pasteurisation,” he says. Raw sprouts Uncooked and lightly cooked sprouts have been linked to more than 30 bacterial outbreaks (mostly of salmonella and E. coli) in the US since mid-1990s. As recently as 2014, salmonella from bean sprouts sent 19 people to the hospital. All types of sprouts - including alfalfa, mung bean, clover and radish sprouts - can spread infection, which is caused by bacterial contamination of their seeds. “There have been too many outbreaks to not pay attention to the risk of sprout contamination,” Marler says. “Those are products that I just don’t eat at all.” He did add that he does eat them if they’re cooked. Meat that isn’t well-done Marler orders his burgers well-done. “The reason ground products are more problematic and need to be cooked more thoroughly is that any bacteria that’s on the surface of the meat can be ground inside of it,” Marler says. “If it’s not cooked thoroughly to 160°F throughout, it can cause poisoning by E. coli and salmonella and other bacterial illnesses.” As for steaks, needle tenderising - a common restaurant practice in which the steak is pierced with needles or sliced with knives to break down the muscle fibres and make it more tender - can also transfer bugs from the surface to the interior of the meat. If a restaurant does this (Marler asks), he orders his steak well-done. If the restaurant doesn’t, he’ll opt for medium-well. Prewashed or precut fruits and vegetables “I avoid these like the plague,” Marler says. Why? The more a food is handled and processed, the more likely it is to become tainted. “We’ve gotten so used to the convenience of mass-produced food - bagged salad and boxed salads and precut this and precut that,” Marler says. “Convenience is great but sometimes I think it isn’t worth the risk.” He buys unwashed, uncut produce in small amounts and eats it within three to four days to reduce the risk for listeria, a deadly bug that grows at refrigerator temps. Raw or undercooked eggs You may remember the salmonella epidemic of the 1980s and early ’90s that was linked mainly to eggs. If you swore off raw eggs back then, you might as well stick with it. The most recent salmonella outbreak from eggs, in 2010, caused roughly 2,000 reported cases of illness. “I think the risk of egg contamination is much lower today than it was 20 years ago for salmonella, but I still eat my eggs well-cooked,” Marler says. Raw oysters and other raw shellfish Marler says that raw shellfish - especially oysters - have been causing more foodborne illness lately. He links this to warming waters, which produce more microbial growth. “Oysters are filter feeders, so they pick up everything that’s in the water,” he explains. “If there’s bacteria in the water it’ll get into their system, and if you eat it you could have trouble. I’ve seen a lot more of that over the last five years than I saw in the last 20 years. It’s simply not worth the risk.” Images: Shutterstock

Food & Wine

15 plants that are poisonous to dogs

<h3>Plants and your pup</h3> Plants are having a real moment right now, and for good reason. They add beauty to your home, help you feel more in tune with nature, and they even boast health benefits. Unfortunately, some of the most popular and best indoor plants are toxic to dogs, who don’t know which ones are safe to munch on or play with and which absolutely aren’t. With veterinary help, we’re calling out the most common indoor and outdoor poisonous plants for dogs so you can avoid or get rid of them and replace them with some pup-friendly options. If you suspect that your pup has munched on a poisonous plant for dogs, consult your vet immediately. <h3>Aloe Vera</h3> Toxic components: saponins, anthraquinones Because it’s so easy to maintain and boasts medicinal qualities, aloe vera is a common household plant that people keep both indoors and outdoors. Unfortunately, the gooey gel beloved for its soothing benefits also contains two components that make this plant toxic to dogs when consumed. Typically, signs of ingestion include lethargy and upset stomach, including vomiting and diarrhoea. If you bring this plant into your home, we recommend keeping it high up – like on a sink ledge – so it’s inaccessible. <h3>Golden Pothos (epipremnum aureum)</h3> Toxic component: insoluble calcium oxalates The winding, ivy-like golden pothos (“Devil’s Ivy”) is another poisonous plant for dogs that contains insoluble calcium oxalates – glass-like crystals that can cause severe irritation when eaten. One of the key symptoms is oral itching and irritation, which can sometimes lead to intense burning and pain in and around your pet’s mouth. It can also lead to excessive drooling, vomiting, or difficulty swallowing. <h3>Milk Weed</h3> Toxic components: cardiotoxins, neurotoxins Though it’s a wonderful beacon for some of our favourite insects – including monarch butterflies and tussock moths – milkweed is one of those plants toxic to dogs. Some species contain cardiotoxins that affect a pet’s heart, while others contain neurotoxins that can affect organ function and mental state. As such, this plant should always be kept outdoors and/or out of reach from your dog. When consumed, it can cause severe reactions, including depression, weakness and diarrhoea, followed by more intense reactions such as seizures, breathing difficulty, organ failure and death. <h3>Sago Palm (cycas revoluta)</h3> Toxic component: cycasin The sago palm is leafy, beautiful and very easy to grow, which makes it a popular choice as an indoor plant. However, this plant’s toxic to dogs, so you should definitely keep it out of your house. “If consumed by your dog, the sago palm causes severe vomiting, diarrhoea and abdominal pain, as well as stumbling, tremors, seizures and temperature-regulation issues,” warns veterinarian Christie Long. “Ultimately, it causes liver failure, and death can occur with ingestion of an amount as small as a single seed.” <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Azaleas (rhododendron)</h3> Toxic component: grayantoxin Azaleas are colourful and interesting to look at, so it’s easy to see why your dog might be attracted to them. Unfortunately, all parts of the azalea plant are poisonous to dogs, including the flower, leaves, seeds and even honey that’s made from the nectar. “When azaleas are consumed by your dog, it can result in hypersalivation, vomiting, diarrhoea, muscle weakness, vision problems, slow heart rate (bradycardia), heart arrhythmia and/or low blood pressure (hypotension), cardiovascular collapse, and possible death,” warns vet Shelly Zacharias. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Tulips (tulipa)</h3> Toxic components: tulipalin A and B Tulips are one of the most popular plants come springtime, but they can cause big problems for curious canines. The flower and stem parts of the plant are toxic, but the bulbs are especially dangerous when consumed. Clinical signs of ingestion include vomiting, diarrhoea, hypersalivation, and even depression. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Garlic and onion (allium species)</h3> Toxic component: n-propyl disulfide Though it’s easy to assume that all vegetables and herbs found in the garden are perfectly OK for your pup, that’s not always true. The allium species – which includes garlic and onions – are poisonous plants for dogs. “Any plant in the allium family, if ingested in large enough quantities, can cause a severe reaction in the bloodstream called hemolysis, in which red blood cells are destroyed in large numbers,” says Dr. Long. “The results are severe weakness, rapid breathing, and red-coloured urine.” She adds that forced vomiting by a veterinarian is key here, and many dogs will require blood transfusions to replace the blood cells that are damaged in order to survive. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Dumb cane (diffenbachia)</h3> Toxic components: insoluble calcium oxalates, proteolytic enzyme This stout, leafy tropical indoor low light houseplant may be pretty, but it should be kept out of reach of canines. “This plant contains calcium oxalate crystals, which are similar to microscopic pieces of glass resembling needles,” explains Dr Zacharias. “Chewing or ingesting it causes toxicity. Common symptoms are vomiting, swelling of the mouth and/or throat, severe oral pain, pawing at mouth or eyes, severe skin irritation, agitation, coughing, gagging and hypersalivation.” Simply coming into contact with the plant can cause symptoms, as well. If your dog’s eyes and skin are exposed, flush immediately or give them a bath. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Elephant’s ear (alocasia)</h3> Toxic component: insoluble calcium oxalates Alocasia – also known as elephant’s ear – is a striking dark green plant commonly found indoors. Like dumb cane, it contains glass-like insoluble oxalate crystals that can cause severe irritation both internally and externally, notes the Pet Poison Hotline. If consumed, an immediate visit to your vet is recommended to monitor and treat symptoms. If your dog’s skin or eyes has become irritated by the plant, a bath and/or flushing the skin and eyes with water is recommended. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Citrus plants and peels (rutaceae family)</h3> Toxic components: essential oils and psoralens “Many [citrus] plants that produce edible fruit – including grapefruit, oranges and lemons – are toxic if the actual plant portion is ingested. For example, the skin of the fruit, the leaves, or stems can often be dangerous,” says Dr Zacharias. Whether you grow these plants in your yard or bring them into your home from the grocery store, keep your dog away from them. Reactions may not be as severe as with other plants toxic to dogs, but if you suspect consumption, call your vet for guidance. They may request that you bring your dog in, especially if severe symptoms occur. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Oleander (nerium oleander)</h3> Toxic component: cardiac glycosides Oleander, known for its white or pink flowers and height that provides privacy between yards, is another poisonous plant for dogs. “Oleander ingestion causes extreme salivation, abdominal pain, vomiting, diarrhoea and lethargy. In severe cases, it causes liver failure and death, and it can ultimately interfere with the heart’s ability to beat properly,” explains Dr Long. “Once it is known that the dog ingested these poisonous leaves, rapid transfer to a veterinary hospital where vomiting can be induced is key. Supportive therapy with drugs designed to control gastrointestinal signs, as well as reverse liver and heart issues, is key to survival.” <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Snake plants (sansevieria trifasciata)</h3> Toxic component: saponins Because of its striking appearance and the fact that it’s a houseplant that’s very hard to kill, snake plants are found in houses all across the world. Unfortunately, they are also poisonous plants for dogs and can cause nausea, vomiting and diarrhoea if consumed. It’s important to contact your veterinarian right away if you think your dog has ingested any portion of a snake plant. Depending on the severity, you may need to simply monitor and treat your dog’s symptoms, or you may need to take your dog in for more aggressive treatment. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Morning glory (ipomoea)</h3> Toxic component: indole alkaloids This beautiful vine plant that flowers in the morning may be irresistible to humans – and also to dogs – who might be tempted to chomp on them when they open. “The seeds are most toxic, and canine consumption can cause vomiting, nausea, pupil dilation (mydriasis), hallucinations, incoordination, diarrhoea, anaemia, confusion and liver failure,” notes Dr Zacharias. Go to your veterinarian or an emergency veterinary centre right away if you suspect consumption. Treatment consists of activated charcoal, IV-fluid administration, and ongoing symptomatic support. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Lily of the valley (convallaria majalis)</h3> Toxic component: cardenolides Lily of the valley is a beloved indoor and outdoor flower, but pet parents should not introduce it to their home or garden since this plant’s toxic to dogs. Known for its delicate white flowers, it is a highly poisonous plant for dogs and can result in vomiting, irregular heartbeat, reduced blood pressure, confusion and disorientation. In severe cases, it can even cause seizures or lead to a coma. Consult your veterinarian immediately for further instruction if you suspect your dog has consumed this plant. <div class="slide-image" style="box-sizing: border-box; border: 0px; font-family: Raleway, sans-serif, Arial; font-size: 16px; font-style: normal; font-weight: 400; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: #444444; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> <h3>Yew (taxus)</h3> Toxic component: taxine Yew is an evergreen shrub typically found outdoors. “If ingested, it can cause sudden death, trembling, muscle weakness, trouble breathing, collapse and heart arrhythmia,” says D. Zacharias. “If you suspect your canine has eaten any part of this plant, immediately go to your veterinarian or emergency veterinary centre. Treatment will consist of gastrointestinal decontamination – activated charcoal or possibly gastric lavage or an enema – as well as IV-fluid therapy and supportive therapy for any respiratory or cardiovascular function.” Image: Getty

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